Some of them have also become the faces of popular clothing brands. The glamour industry is seeing a major shift towards body positivity and becoming inclusive.
Here's a look at how the spirit of humanity is being celebrated in the sartorial world:
Message of peace
At a recently-concluded fashion week in Tokyo, designer Takafumi Tsuruta roped in models from different walks of life to depict the adverse effects of nuclear weapons. Disabled comedian Yusei Terada, visually-challenged accordion player Sota Nii and Akako Ozawa, a singer with muscular dystrophy, wore the designer's creations.
Small is beautiful
Bucking the fashion show stereotype of tall, willowy models, earlier this month 15 women, less than four feet four inches tall, walked the runway at a special fashion show in Paris. Some time back, the same show was held in New York. It will be organised in Tokyo next year
American model Ashley Graham has featured on the covers of several fashion magazines and in the campaign of a leading denim brand. She was the first plus-size model to be featured in a sports magazine's swimsuit issue. This year, she partnered with a Canadian plus-size clothing retailer to launch her own line of lingerie.
Against all challenges
Rebekah Marine, a 28-year-old model from New Jersey who was born without a right forearm and wears an i-limb quantum prosthetic hand, participated in a fashion week in New York last month.Jamie Brewer, an actress, activist and model who has Down syndrome, also walked the ramp.
Canadian model Chantelle BrownYoung, also known as Winnie Harlow or Chantelle Winnie, who suffers from the chronic skin condition vitiligo, featured in an Italian clothing brand's SpringSummer campaign earlier this year. She is also the brand representative of a Spanish casual clothing brand.